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翟金霞


翟金霞

邮箱:jinxia.zhai@foxmail.com

职称:副教授

办公室地址:安徽省合肥市蜀山区梅山路81号行知楼B座,230032

研究领域描述

精子发生和成熟是男性生育能力的重要前提,对于各种环境内分泌干扰物的精子发生和成熟毒性研究是理解男性不育的关键,也是将环境内分泌干扰物毒性研究应用数世纪的防控工作的前提。本课题组主要围绕十溴联苯醚,分布广泛的环境内分泌干扰物和男(雄)性生殖毒物一种环境内分泌干扰物,对于雄性生殖细胞的毒性效应、精子发生和成熟的调控机制,特别是表观遗传调控机理,以及相关的生殖系细胞发育过程中的表观遗传学重编程机理。并在此基础上深入探索雄性生殖细胞发育异常相关的不育症等疾病的分子机理,为制定相关的防治对策和措施提供理论基础。

 

代表性论文:

1. Jinxia Zhai, Xiya Geng, Tao Ding, Jun Li, Jing Tang, Daojun Chen, Longjiang Cui, Qizhi Wang. An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice. Environmental Science and Pollution Research, 2018, 26(5): 4801-20. 

2. Jing Tang, Jinxia Zhai*. Distribution of polybrominated diphenyl ethers in breast milk, cord blood and placentas: a systematic review. Environmental Science and Pollution Research, 2017, 24(27): 21548-73. *corresponding author

3. JinXia Zhai, Zhao-Xiang Zhang, Ya-Juan Feng, Shu-Shu Ding , Xing-Hua Wang,  Li-Wei Zou. PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr Mice [J]. Molecular biology reports, 2012, 39(6): 6763-71

4. Jixiang Xu,Wenfeng Geng, Xiya Geng, Longjiang Cui, Jing Tang, Changchun Xiao, Junqing Zhang, Jinxia Zhai*. Study on the association between ambient air pollution and daily cardiovascular death in Hefei, China. Environmental science and pollution research international, 2020, 27(1): 547-61. *corresponding author

5.Longjiang Cui, Xiya Geng , Tao Ding, Jixiang Xu, Jing Tang, Jinxia Zhai*. Impact of ambient temperature on hospital admissions for cardiovascular disease in Hefei City, China. Int J Biometeorol, 2019, 63(6): 723-34. *corresponding author

6. Jing Tang, Chang-chun Xiao, Yu-rong Li, Jun-qing Zhang, Hao-yuan Zhai, Xi-ya Geng, Rui Ding, Jinxia Zhai*. Effects of diurnal temperature range on mortality in Hefei city, China . International Journal of Biometeorology, 2017, 62(5): 851-60. *corresponding author